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"The Use of Ascorbic Acid in Preventing and Treating Disease," Autograph Manuscript Signed, 26 individual sheets of lined paper, 4to, "Linus Pauling Institute of Science and Medicine," Menlo Park, CA, n.d. but 1970s
Pauling makes a clear argument for the use of Vitamin C to protect against the common cold. He offers a chronological review of research throughout this readable paper suggesting that Vitamin C research was ignored in favor of promoting sulfa based drugs and antibiotics. Pauling notes in the corner of the title page that the document is 2200 words long. The title page contains Pauling's signature as the author of the paper, "Linus Pauling" and in the title of the Pauling Institute. Fine condition throughout with paper clip rust marks on the title and final pages, written on every other line in a legible hand. "When pure L-ascorbic acid (vitamin C) became available about forty years ago many studies were carried out to obtain information about its value in improving health and protecting against disease. It was soon shown that an intake of a few milligrams per day sufficed to prevent the development of scurvy in most people This fact is the basis for the value of the recommended allowance (the RDA now 45 mg for an adult) of the Food and Nutrition Board of the United States National Academy of Sciences - National Research Council...." Other scientists asked "what daily intake would lead to the best of health" and whether "large doses would be helpful in the treatment of existing diseases...For some time there was considerable use of large doses of ascorbic acid and of other vitamins in the treatment of patients. A change of attitude then occurred. It began to be said that a high intake of ascorbic acid had no value in the prevention or treatment of the common cold or any other disease...." He quotes the conclusion of this research and disagrees. "The statement that these claims have not withstood the test of time is wrong...the nutritional and medical authorities decided to ignore the evidence...." He explains that there was greater interest in "sulfa drugs and antibiotics, with their great effectiveness and reliability against infectious diseases contributed to the loss of interest in Vitamin C and other vitamins...." He offers some of his personal history studying Vitamin C beginning in 1966, referencing research papers and his 1970 book which summarized this research, "Vitamin C and the Common Cold." In the next section titled, "The Common Cold," Pauling reviews the research on Vitamin C's efficacy. "Many people have been misled by unjustified and unsupported statements that studies of ascorbic and the common cold have given negative results ...." After he presents examples from research papers he argues that tables were inaccurately interpreted. "Moreover, there was a serious flaw in the design of the study. The administration of tablets was stopped on average of three days after the onset of the colds, and the colds lasted an average of five days longer. We know that when a large intake of ascorbic acid is suddenly stopped the concentration in the blood drops for a few days to an abnormally low level...the abnormally low concentration of ascorbic acid decreases the effectiveness of the mechanisms of protection and may lead to exacerbation of the viral infection and the development of a secondary bacterial infection...." "The Action of Ascorbic Acid," is the title of the next section. Pauling's thesis in this section is that ascorbic acid stimulates and strengthens the body's "natural defense mechanisms." He references the relevant research papers and indicates that in a particular hospital some "surgical patients and intensive-care patients...now receive 6 to 10g of ascorbic acid per day...." He notes the source of this information is "personal communication" from the doctor. Pauling titles the final section, "Summary and Conclusion." "The evidence is now overwhelming that an increased intake of ascorbic acid provides a significant amount of protection against the common cold...the optimum daily intake...probably lies between 1g and 10g for most people (Pauling 1974)...Ascorbic acid has very low toxicity and few side effects...." Finally Pauling recommends that more "trials" should be done because Vitamin C's potential "is so great.".
      [Bookseller: Schulson Autographs]
Last Found On: 2017-10-24           Check availability:      Biblio    

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