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Tractatus de ventriculo et intestinis. Cui praemittitur alius, de partibus continentibus in genere & in specie, de iis abdominis.
Amstelodami : Apud Jacobum Juniorem (i.e. Jansson-Waesberge), 1677, 12, Gestochenes Portrait-Frontispiz, (32), 591, (1) pp., 3 Kupfertafeln, Pergamenteinband der Zeit mit handschriftlichem Rückentitel Titel kleiner Auschnitt hinterlegt. First edition printed in the European continent of Glisson's rare work on the digestive organs and internal tissues! With Coat of Arm ExLibris " Iacob Reinbold Spielmann", J. Striedbeck. del. et sculp: Argent.Francis Glisson (1597-1677) "introduced the idea of irritability as a specific property of all human tissue, a hypothesis which had no effect upon contemporary physiology, but which was later demonstrated experimentally by Haller". Garrison & Morton"Stimulated by ideas of his friend George Ent, Glisson elaborated a theory which he revised in his last medical work, the Tractatus de ventriculo et intestinis (1677). The theory presented itself as follows: The nerves carry a nutritive juice (succus nutrivus) secreted by the brain between cortex and medulla from particles of the arterial blood. The psychic spirits are the "fixed spirits" of this juice, which serves nutrition rather than the function of body fibers. As a chemical substance, the psychic spirits cannot flow fast enough to assure simultaneity of events in the brain and the peripheral parts. Nerve action is transmitted by a vibration of the nerves (caused by localized contraction of the brain), and the muscle fibers then contract because of irritability, a property which they share with all fibers of the body". Owsei Temkin, p.426"The doctrine of irritability does not exhaust the content of the Tractatus de Ventriculo et Intestinis, which, apart from the treatise indicated by the title, also contains a treatise on skin, hair, nails, fat, abdominal muscles, peritoneum, and omentum. Together the Anatomia hepatis and the Tractatus de Ventriculo et Intestinis constitute a monumental work on general anatomy and on anatomy and physiology of the digestive organs. Moreover, in the latter treatise [offered here], Glisson goes far beyond the stomach and intestinal tract. Apart from discussing the theory of digestion , Glisson manages to include theories of embryogenesis (in which the relationship to Harvey is particularly interesting)". Owsei Temkin, p.427Garrison & Morton No. 579 (London 1677) Owsei Temin, DSB V, pp.425-427 Heirs of Hippocrates 475 (citing 1691 edition). Rothschuh, History of Physiology, pp. 86-87 Krivatsy 4829 Waller 3587 Wellcome III, 126
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