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Die Aetiologie der Milzbrand-Krankheit, begründet auf die Entwicklungsgeschichte des Bacillus Anthracis (pp.277-310, 1 Taf.). + Cohn, F.: Beiträge zur Biologie der Bacillen (pp.250-276, 1 Taf.). *)
Beitr. Biol. Pflanz., 2/2. - Breslau, J.U. Kern's Verlag (Max Müller, 1876, 8,(4), pp.123-310, mit fünf zum Teil farbigen Tafeln, Halbledereinband der Zeit Rücken erneuert feines Exemplar. First Edition of two Milestones of Microbiology! In 1876 Robert Koch (1843-1910) first obtained pure cultures of B.anthracis and described its complete life history. With Davaine (No.5165-66) he did much to prove that infectious diseases are caused by living reproductive micro - organisms. The postulates expounded by Koch on this occasion had fundamental importance and have become the bases on which bacteriology largely rests. The paper also marks the beginning of exact knowledge of bacterial infectious diseases. It is reproduced with translation in Med. Classics, 1938, 2, 745-820.Milestones in Microbiology, Ed. by. Thomas Brock (1961), pp.89-95 Garrison & Morton No.5167*) "Ferdinand Cohn "clearly saw that not all liquids or solids are sterilized easily. Instead of using this information to accept or reject the theory of spontaneous generation, he decided to find out what was responsible for this observations. His experiment with hay infusion was an enrichment culture. By boiling for a while, he killed all organisms that were sensitive to boiling water. Only heat resistant forms were left, and these could develop and he studied under the microscope. In this way he discovered a new species, Bacillus subtilis, and a new process, spore formation ... We know now that bacterial spores are the most heat resistant of all living organism ... We can also see here in Cohn's work the beginnings of the development of bacteriological techniques, such as the use of cotton for closing flasks and tubes. But probably the most important result of this work is that it was the direct forerunner of Koch brilliant researches on infectious disease." Milestones in Microbiology, Ed. by. Thomas Brock (1961), pp.49-56
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