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Sulla struttura degli epiteli pavimentosi stratificati.
- Rendiconti del Reale Istituto Lombaro, serie II, Voll. III. Fasc. XVI. - Milano 1870, 8°, 8 pp., 2 Taf., feiner Pappband. Very rare offprint! - - "Nodes of Bizzozero in the skin. Another field of interest for Bizzozero concerned the histological structure of the epidermis and, in particular, the points of contact between adjacent cells of the stratum spinosum, erroneously considered at the time to be 'intercellular bridges' that established a cytoplasmic continuity. Bizzozero's attention was captured by some peculiar shapes that he observed in these cells, such that the processes projecting from the adjacent cellular elements met end-to-end in small, dense and dark nodules, later known as 'nodes of Bizzozero'. Bizzozero perceptively concluded that there was no cytoplasmic continuity between these cells, and that the dense nodules that we now call desmosomes or 'connecting bodies' (from the Greek words desmos for 'bond' or 'ligament' and soma for 'body'), were, in fact, bipartite adhesive structures to which both cells contributed. Bizzozero's conclusion was not accepted at the time, owing to the influence of Louis Ranvier, who propounded the opposite idea of cell-to-cell continuity. The definitive resolution of this controversy came with the advent of the electron microscope, which revealed a protoplasmic discontinuity at the level of the intercellular bridges, so confirming Bizzozero's theory." Paolo Mazzarello, Alessandro L. Calligaro & Alberto Calligaro: Timeline: Giulio Bizzozero: a pioneer of cell biology. Nature Reviews Molecular Cell Biology 2 (2001/10), pp.776-784 - - See - - Bizzozero, G. Delle cellule cigliate del reticolo malpighiano dell'epidermide delle mucose e dei cancroidi. Ann. Univ. Med. 54, 111-118 (1864). - Bizzozero, G. Ueber den Bau der geschichteten Plattenepithelien in Le Opere Scientifiche di Giulio Bizzozero 1, 237-243 (Hoepli, Milano, 1905). - Bizzozero, G. Sulla struttura degli epiteli pavimentosi stratificati. Arch. Sci. Med. 9, 373-378 (1885). - Bucciante, L. Istologia (Cedam, Padova, 1973). - Fawcett, D. W. The Cell (W. B. Saunders, Philadelphia, 1981). - Zelickson, A. S. Ultrastructure of Normal and Abnormal Skin (Lea & Febiger, Philadelphia, 1967). [Attributes: Hard Cover]
      [Bookseller: Antiq. F.-D. Söhn - Medicusbooks.Com]
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