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2020-11-22 18:41:51
Magendie, Francois
Recherches physiologiques et cliniques sur l'emploi de l'acide prussique ou hydro-cyanique dans le traitement des maladies de poitrine, et articulièrement dans celui de la phthisie pulmonaire;
Paris, Chez Méquignon-Marvis, 1819, 8°, 72 pp., orig. Interimsbroschur; feines unbeschnittenes Epl. Rare - First Edition! Early and Important step towards modern Pharmacology! This is "A more interesting case of the relation between his experimental activities and his medical practice is his memoir of 1817 *), on the use of prussic acid in pulmonary phthisis. Gay-Lussac at this time was making his classic researches on hydrocyanic acid and Magendie described how this deadly chemical agent killed a dog so quickly that it was almost as if the animal were struck by lightning. The drug was already in clinical use in pulmonary diseases, but because it was lethal in very small quantities Magendie thought that adoption of the method of Gay-Lussac in its preparation would contribute to precision in the assessment of dosage. In M. Pelletier's laboratory he himself prepared some of this acid so that he might be sure of its purity and administered it, greatly diluted, to one of his patients who was troubled with a dry cough every morning and night. The treatment was a complete success. He tried the remedy on fifteen other patients, in all cases with success. Finally, he persuaded Dr. Lerminer at the Charité to use hydrocyanic acid on twenty patients in his wards, and together the two physicians were watching the results at the time the memoir was read. The paper was soon (1820) 5 translated into English for the benefit of American physicians. The small pamphlet was printed in New Haven, Connecticut, and bore the stamp of approval of the famous Benjamin Silliman, Professor of Chemistry … [Click Below for Full Description]
Bookseller: Antiq. F.-D. Söhn - Medicusbooks.Com [Marburg, Germany]
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