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On the constitutional and local effects of disease of the supra-renal capsules
London Highley 1855 "The Perfect Description of an Endocrine Disease"Addison, Thomas (1793-1860). On the constitutional and local effects of disease of the supra-renal capsules. 4to. viii, 43, [1]pp. 11 hand-colored lithograph plates. London: Samuel Highley, 1855. 327 x 250 mm. Original green cloth stamped in gilt and blind, slightly worn, skillfully recased retaining original endpapers, preserved in a half morocco drop-back box. A little light foxing, stamp on title, but a very fine, bright copy.First Edition. "The perfect description of an endocrine disease" (Medvei, p. 226), and one of the most important rarities of 19th century medical literature. Addison§s monograph inaugurated the study of diseases of the ductless glands and the disturbances in chemical equilibrium known as pluriglandular syndromes; it also marks the beginning of modern endocrinology. The present monograph focuses on diseases of the suprarenal capsules and contains the classic description of the endocrine disturbance now known as "Addison§s disease," and also includes his superb account of pernicious anemia ("Addison§s anemia"), in which he suggested that the existence of anemia together with supra-renal disease was not coincidental. Addison was the first to suggest that the adrenal glands are essential for life, and his monograph inspired a burst of experimental research that led, among other things, to Vulpian§s discovery of adrenalin in 1856. Garrison-Morton 3864. Norman / Grolier Medical Hundred 60c. Heirs of Hippocrates 1502. Goldschmid, Bibliographie der pathologisch-anatomischen Abbildung, p. 194. McCann, pp. 87-89. Medvei, pp. 225-230. Norman 8.
      [Bookseller: Jeremy Norman]
Last Found On: 2012-12-27           Check availability:      Direct From Bookseller    

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