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Charles Nicolle, Nobel Laureate, writes an - Louis Pasteur - 1885. 
Tunis, Africa, August 14, 1885. 5.25" x 8". "Four page letter, with one side left blank. 5.25"" x 8"", on stationary with letterhead of Institut Pasteur de Tunis. Signed ""C. Nicolle"", and dated ""Tunis 14 aout 1885"" (Tunis August 14, 1885). Expected center fold. Fine condition. Accompanied by an English translation.This early letter was written by Charles Nicolle in 1885 from the Institut Pasteur in Tunis Africa, and referred to his measles research before he received his MD in 1893, and in advance of his published measles findings. In his letter he states (as translated in English) that 'I will mail to your colleague, you gave me the address, my last publication of the measle prevention'. Later, Nicolle would discover that by injecting children with convalescent serum, it would prophylactically protect them from the disease for 2 - 4 weeks. This period would be long enough to protect family members from each other who had the disease, or for use in institutional settings and outbreaks. His other research was on Typhus, where Nicolle would ultimately make his major breakthrough and obtain the Nobel Prize in Medicine in 1928 . Nicolle was appointed Director of the Pasteur Institute in Tunis, a position he held until his death in 1936. Under his influence, the Institute at Tunis quickly became a world famous center for bacteriological research and for the production of vaccines and serums to combat most of the prevalent infectious diseases. Nicolle's research on Typhus culminated in the discovery on the mechanism of the transmission and the vector of the disease, which allowed for preventive precautions to be put in place against the disease during the 1914 - 1918 and 1939 - 1945 Wars.A wonderful fine condition letter by one of the leading research scientists in early bacteriological studies on infectious diseases. His invaluable contributions include present day knowledge of Malta fever, where he introduced preventive vaccination; tick fever, where he discovered the means of transmission; scarlet fever, by experimental reproduction with streptococci; rinderpest, measles, influenza, by his work on the nature of the virus; tuberculosis and trachoma. He was responsible for the introduction of many new techniques and innovations in bacteriology. We were only able to find one other letter of Nicolle selling at auction in the past 4 decades. The letter sold for over $1,000 but was written 48 years after our letter, was not on Pasteur stationary and was about evolution as opposed to the topics he discusses in our letter, which is what brought him fame."
[Bookseller: University Archives]
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