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Ãber Spinalganglien und RÃ¼ckenmark des Petromyzon - Freud, Sigmund - 1878. 
1878 - Freud, Sigmund (1856-1939). Ãber Spinalganglien und RÃ¼ckenmark des Petromyzon. Offprint from Sitzungsberichte der kaiserlichen Akadademie der Wissenschaften, 3 Abth., 78 (1878). [Vienna: K.k. Hof- und Staatsdruckerei, 1878.] 87pp. 4 folded lithographed plates by F. Schima after Freud. 247 x 158 mm. Original brown printed wrappers, edges and extremities a bit chipped, tear in corner of back wrapper. Very good. Presentation Copy, inscribed by Freud to Josef Herzig (1853-1924) on the front wrapper: "Seinem lieben Freunde Herrn Chem. Dr. J. Herzig d. Verf." The Haskell F. Norman copy, with his bookplate. First Edition, Rare Offprint Issue. In 1876, three years after entering the University of Vienna as a medical student, Freud joined the laboratory of the eminent physiologist Ernst BrÃ¼cke where he began studying the histology of nerve tissue, a subject that would occupy him for the next ten years. During this time Freud published his earliest scientific papers, in which he made several significant contributions to our knowledge of the structure of nerve cells and took some first steps toward the theory of the neuron. Freuds first assignment at BrÃ¼ckes lab was to clarify the structure of the so-called Reissner cells, a large type of nerve cell found in the spinal cord of the lamprey (Petromyzon), a primitive species of fish. "Within a few weeks, Freud reported to BrÃ¼cke that he could not only trace peripheral sensory nerves to their origins from Reissners cells, but he could also see fibers in the dorsal (sensory) roots that arose from these same cells and passed centrally into the spinal cord. This led to his first scientific papers, in which he concluded that Reissners cells are nothing else than spinal ganglion cells which, in those low vertebrates, where the migration of the embryonic neural tube to the periphery is not yet completed, remain within the spinal cord" (Shepherd, Foundations of the Neuron Doctrine: 25th Anniversary Edition, pp. 66-67). Freuds first paper on Petromyzon appeared in 1877. In his second Petromyzon paper, which we are offering here, Freud made a major contribution to evolutionary biology by showing that the spinal ganglion cells of Petromyzon represent a transition between the bipolar cells of lower and the unipolar cells of higher vertebrates. "In other words, the observations in Petromyzon enabled one to construct an evolutionary sequence for dorsal root ganglion cells, from the bipolar form, to transitional forms that are either bipolar or unipolar, to strictly unipolar forms as seen in the higher vertebrates" (Shepherd, p. 67). Freud presented this copy to Josef Herzig, professor of chemistry at the University of Vienna and one of Freuds lifelong friends. Gay, Freud: A Life for our Time. Grinstein 34. Jones I, pp. 52-53. Norman F3. [Attributes: First Edition; Signed Copy; Soft Cover]
[Bookseller: Jeremy Norman's historyofscience]
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